Alcet 5mg

Indication

Allergic rhinitis, Allergic conditions, Chronic idiopathic urticaria

Administration

May be taken with or without food.

Adult Dose

Oral Seasonal allergic rhinitis, Chronic idiopathic urticaria Adult: 5mg once daily

Child Dose

Oral Seasonal allergic rhinitis, Chronic idiopathic urticaria Children 12 years of age and older: 5mg once daily Children 6 to 11 years of age: 2.5mg (1/2 tablet or 1 teaspoon oral solution) once daily Children 6 months to 5 years of age: 1.25 mg (1/2 teaspoon oral solution) once daily

Renal Dose

Renal Impairment CrCl 50-80 mL/min: 2.5 mg PO qDay CrCl 30-50 mL/min: 2.5 mg PO qOD CrCl 10-30 mL/min: 2.5 mg PO 2x/wk CrCl <10 mL/min: contraindicated

Contraindication

Patients who are hypersensitive to this medication or any of its ingredients.

Mode of Action

Levocetirizine is an active isomer of cetirizine which selectively competes for w/ histamine for H1-receptor sites on effector cells in the GI tract, blood vessels, and resp tract.

Precaution

Epileptic patients and patients at risk of convulsions. Renal impairment. Pregnancy and lactation. Patient Counselling May impair the ability to drive or operate machinery. Monitoring Parameters Monitor CrCl before treatment for dosage adjustment. Lactation: expected to be excreted in breast milk, avoid

Side Effect

1-10% Dry mouth, Fatigue, Nasopharyngitis, Pharyngitis Frequency Not Defined Somnolence, dizziness, pyrexia, cough, epistaxis, diarrhea, vomiting, constipation, otitis media, dysuria, urinary retention, blurred vision, angioedema, paraesthesia, dystonia, oculogyric crisis, myoclonus, extrapyramidal symptoms.

Interaction

Possible additive adverse CNS effects w/ CNS depressants (e.g. sedatives, tranquilizers).