|Company:||Healthcare Pharmaceuticals Ltd.|
Allergic rhinitis, Allergic conditions, Chronic idiopathic urticaria
May be taken with or without food.
Oral Seasonal allergic rhinitis, Chronic idiopathic urticaria Adult: 5mg once daily
Oral Seasonal allergic rhinitis, Chronic idiopathic urticaria Children 12 years of age and older: 5mg once daily Children 6 to 11 years of age: 2.5mg (1/2 tablet or 1 teaspoon oral solution) once daily Children 6 months to 5 years of age: 1.25 mg (1/2 teaspoon oral solution) once daily
Renal Impairment CrCl 50-80 mL/min: 2.5 mg PO qDay CrCl 30-50 mL/min: 2.5 mg PO qOD CrCl 10-30 mL/min: 2.5 mg PO 2x/wk CrCl <10 mL/min: contraindicated
Patients who are hypersensitive to this medication or any of its ingredients.
Mode of Action
Levocetirizine is an active isomer of cetirizine which selectively competes for w/ histamine for H1-receptor sites on effector cells in the GI tract, blood vessels, and resp tract.
Epileptic patients and patients at risk of convulsions. Renal impairment. Pregnancy and lactation. Patient Counselling May impair the ability to drive or operate machinery. Monitoring Parameters Monitor CrCl before treatment for dosage adjustment. Lactation: expected to be excreted in breast milk, avoid
1-10% Dry mouth, Fatigue, Nasopharyngitis, Pharyngitis Frequency Not Defined Somnolence, dizziness, pyrexia, cough, epistaxis, diarrhea, vomiting, constipation, otitis media, dysuria, urinary retention, blurred vision, angioedema, paraesthesia, dystonia, oculogyric crisis, myoclonus, extrapyramidal symptoms.
Possible additive adverse CNS effects w/ CNS depressants (e.g. sedatives, tranquilizers).