What are the worst side effects of citalopram?

Citalopram, like many medications, can have a range of side effects, and their severity can vary from person to person. While most people tolerate citalopram well, some individuals may experience more serious or bothersome side effects. Some of the potential worst or severe side effects of citalopram include:

  1. Serotonin Syndrome: This is a rare but potentially life-threatening condition that can occur when there is an excessive buildup of serotonin in the brain. Symptoms can include confusion, hallucinations, rapid heartbeat, fever, extreme changes in blood pressure, and seizures. If you experience these symptoms, seek immediate medical attention.
  2. Allergic Reactions: While uncommon, some people may have allergic reactions to citalopram. Signs of an allergic reaction can include rash, itching, swelling, severe dizziness, and difficulty breathing. Seek medical help if you suspect an allergic reaction.
  3. Suicidal Thoughts: In some cases, especially in children, teenagers, and young adults, citalopram and other antidepressants may increase the risk of suicidal thoughts and behaviors, especially when treatment is first started or the dosage is adjusted. It’s important to closely monitor individuals taking citalopram, especially at the beginning of treatment.
  4. Withdrawal Symptoms: Stopping citalopram abruptly can lead to withdrawal symptoms, including dizziness, nausea, fatigue, and “electric shock” sensations in the brain. It’s important to taper off the medication under a healthcare provider’s supervision to minimize these effects.
  5. Changes in Heart Rhythm: Citalopram can, in rare cases, cause changes in the electrical activity of the heart, leading to a condition called QT prolongation. This can increase the risk of a potentially life-threatening irregular heartbeat (arrhythmia). Individuals with a history of heart problems or those taking other medications that affect heart rhythm may be at greater risk.
  6. Sexual Side Effects: Some people may experience sexual side effects while taking citalopram, including decreased libido, difficulty achieving or maintaining an erection (erectile dysfunction), or delayed ejaculation. These side effects can be distressing for some individuals.
  7. GI Disturbances: Citalopram may cause gastrointestinal symptoms such as nausea, diarrhea, or constipation in some people.
  8. Sleep Disturbances: Sleep-related side effects, such as insomnia or drowsiness, can occur while taking citalopram. These effects can vary between individuals.

It’s essential to discuss any side effects or concerns with your healthcare provider. They can help assess the risks and benefits of citalopram in your specific situation and may adjust the dosage or recommend alternative treatments if necessary. It’s also crucial to follow your provider’s instructions regarding the medication and attend follow-up appointments to monitor your progress and any potential side effects. Never stop taking citalopram or any antidepressant suddenly without consulting your healthcare provider, as this can lead to withdrawal symptoms.

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