|Company:||Drug International Ltd.|
|Generic:||Vitamin E (Alpha-tocopherol)|
Cardiovascular disease, Male infertility, Diabetes, Obesity, Vitamin E deficiency, Peripheral neuropathy, Macular Degeneration
Oral Adult: Betterment of Cardiovascular health: 400 mg – 800 mg/day Deficiency syndrome in adults: 200 mg – 400 mg/day Thalassemia: 800 mg/day Sickle-cell anemia: 400 mg/day Betterment of Skin & Hair: 200 mg – 400 mg/day. Chronic cold in adults: 200 mg/day
Oral Deficiency syndrome in children: 200 mg/day
There is no absolute contraindication except known hypersensitivity to vitamin E.
Mode of Action
Vitamin E plays a role in protecting red blood cells against hemolysis; has protective effects against free radicals on polyunsaturated fatty acids found in cell membranes; plays a role in preventing oxidation of vitamins A and C.
Vitamin E may enhance the anticoagulant activity of anticoagulant drugs.
Fatigue, Headache, Flatulence, Diarrhea, Blurred vision, Necrotizing enterocolitis (infants), Increased serum creatinine, and Increased risk of hemorrhagic stroke, Recent evidence suggests that Vitamin E may suppress the action of other antioxidants
Colestyramine, colestipol, and orlistat may interfere with vitamin E absorption. High doses of vitamin E potentiate the anticoagulant action of warfarin. Large doses of vitamin E may impair response to iron supplementation.