| Specifications | |
|---|---|
| Company: | Square Pharmaceuticals Ltd. |
| Generic: | Aceclofenac |
| Price: | 50tk bd |
Introduction
Flexi 100 is a pain-relieving medicine. It alleviates pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Flexi 100 should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. Vomiting, stomach pain, nausea, and indigestion are some of the common side effects that might be observed on taking this medicine. It may also cause dizziness, drowsiness, or visual disturbances. Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems. Flexi 100 is not recommended if you are pregnant or breastfeeding.
Uses of Flexi 100
- Pain relief
Side effects of Flexi 100
Common
- Vomiting
- Stomach pain/epigastric pain
- Nausea
- Indigestion
- Diarrhea
- Heartburn
- Loss of appetite
How to use Flexi 100
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Flexi 100 is to be taken with food.
How Flexi 100 works
Flexi 100 is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
Quick Tips
- You have been prescribed Flexi 100 to relieve pain and inflammation.
- Take it with food or milk to prevent an upset stomach.
- Take it as per the dose and duration prescribed by your doctor. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
- It may cause dizziness, drowsiness, or visual disturbances. Use caution while driving or doing anything that requires concentration.
- Avoid consuming alcohol while taking Flexi 100 as it can cause excessive drowsiness and increase your risk of stomach problems.
- Inform your doctor if you have a history of heart disease or stroke.
- Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
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Brief Description
Indication
Adult: PO Ankylosing spondylitis; Osteoarthritis; Rheumatoid arthritis 100 mg twice daily. SR Tablet : The recommended dose is 200 mg, once daily. Elderly: The pharmacokinetics of aceclofenac are not altered in elderly patients, therefore it is not considered necessary to modify the dose and dose frequency. Hepatic Impairment Reduce the initial dose to 100 mg daily.
Administration
May increase plasma concentrations of lithium and digoxin. Increased nephrotoxicity when used with diuretics or ciclosporin. Monitor serum potassium when used with potassium-sparing diuretics and ACE inhibitors. May enhance the activity of anticoagulants. May increase the risk of methotrexate toxicity when administered within 24 hr of methotrexate admin. Increased risk of GI bleeding with other NSAIDs. Increased risk of convulsion with quinolones.
Adult Dose
Cautiously administer to patients with GI disease, ulcerative colitis, Crohn’s disease, hematological abnormalities, hepatic porphyria; history of bronchial asthma; history of heart failure or hypertension; mild renal, hepatic, or cardiac impairment. May impair the ability to drive or operate machinery. Elderly. Patients suffering from severe hepatic impairment must be monitored.
Renal Dose
Aceclofenac, a phenylacetic acid derivative, has anti-inflammatory and analgesic properties. It is a potent inhibitor of cyclo-oxygenase which is involved in the production of prostaglandins.
Contraindication
Safety & Efficacy not established.
Mode of Action
Should be taken with food. Take w/ or immediately after meals.
Precaution
Indicated for the relief of pain and inflammation in both acute and chronic pain like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, post-traumatic pain, low back pain, and gynecological pain.
Side Effect
No dose adjustment is needed.
Pregnancy Category Note
Gastrointestinal disorders (dyspepsia, abdominal pain, nausea, and diarrhoea) and occasional occurrence of dizziness. Dermatological side effects include pruritus and rash. Abnormal hepatic enzyme levels and raised serum creatinine have occasionally been reported. Potentially Fatal: Severe GI bleeding; nephrotoxicity; blood dyscrasias.
Interaction
Hypersensitivity to aspirin or NSAIDs; moderate to severe renal impairment; pregnancy (3rd trimester); history of peptic ulceration or GI bleeding; patients with infections.