K MM

Introduction

K MM is a medicine used to treat vitamin K deficiency in the body. It helps in improving conditions caused due to low levels of vitamin K in the body. Vitamin K is an important nutrient that is necessary for blood clotting and bone metabolism. K MM is given under the supervision of a healthcare professional and should not be self-administered. You should take it regularly to get the most benefit from it. This medicine may be only part of a complete program of treatment that also includes making changes to your diet and taking vitamin supplements. K MM is generally safe with little or no side effects. However, it may cause pain, redness, or swelling at the site of injection in some people. Before taking this medicine, let your doctor know all other medicines you are taking to make sure you are safe. It is important to ask for advice from the doctor before taking any other vitamin supplements.

Uses of K MM

• Nutritional deficiencies

Side effects of K MM

Common

• No common side effects seen

How to use K MM

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How K MM works

K MM is a synthetic form of vitamin K. It restores the activity of vitamin K and speeds up the normal blood clotting process to prevent or treat bleeding caused due to too high a dose of warfarin.

Quick Tips

• Do not use phytomenadione if you have glucose-6-phosphate dehydrogenase (G6PD) deficiency (a disorder in which the red blood cells are destroyed faster leading to anemia).
• Do not use it as an antidote for heparin.

Brief Description

Indication

Vitamin K deficiency, Over-anticoagulation, Vitamin K deficiency bleeding

Administration

May be taken with or without food.

Adult Dose

Oral Vitamin K deficiency due to drugs or malabsorption Adult: 10-40 mg daily. Over-anticoagulation Adult: Up to 5 mg may be used. The dose depends on INR and the degree of hemorrhage. Intravenous Over-anticoagulation Adult: 0.5-5 mg via slow IV in. The dose depends on INR and the degree of hemorrhage.

Child Dose

Intramuscular Prophylaxis of vitamin K deficiency bleeding in neonates Child: Neonate: 0.5-1 mg, given as a single dose via IM in. Alternatively, 2 mg may be given orally, followed by a 2nd dose of 2 mg after 4-7 days. Parenteral Vitamin K deficiency bleeding in neonates Child: Infant: 1 mg by IV/IM/SC inj, further doses may be given if necessary

Contraindication

Hypersensitivity.

Mode of Action

Phytomenadione promotes the hepatic synthesis of clotting factors. It is a naturally occurring compound that is used to prevent and treat hemorrhages related to vitamin K deficiency.

Precaution

Increased risk of severe hemolytic anemia in neonates after large doses; severe hepatic impairment; pregnancy. Premature neonates weighing <2.5 kg. Lactation: Excreted in breast milk; use caution

Side Effect

Anaphylaxis, dyspnoea, cyanosis, pain, swelling, phlebitis at the Inj site, diaphoresis, dizziness, hypotension (rare), allergic reactions after SC and IM in.

Interaction

Decreased effect of oral anticoagulants.